Sensitivity and Specificity To prepare for this Discussion, review the Learning Resources for this week. By Day 4, a comprehensive response to the following: You have been asked to conduct a clinical trial to test the efficacy of a new drug for treating condition Q. You first need to identify a sample of subjects who test positive for the condition, then randomly assign them to treatment and placebo groups. After 10 weeks you will retest both groups to compare the percentage of subjects in each group who test positive for condition Q. Before beginning the trial, you have to choose one of two tests to detect the presence of condition Q. Test A has a sensitivity of 95% and specificity of 75%. Test B has sensitivity of 75% and specificity of 95%.Document your assumptions. Which test would you choose for the trial and why? Read a selection of your colleagues’ postings. By Day 6, respond to at least one of your colleagues’ postings in one or more of the following ways: Ask a probing question. Expand on the colleague’s posting with additional insight and resources. Offer polite disagreement or critique, supported with evidence. In addition, you may also respond as follows: Offer and support an opinion. Validate an idea with your own experience. Make a suggestion or comment that guides or facilitates the discussion. Return to this Discussion in a few days to read the responses to your initial posting. Note what you have learned and/or any insights you have gained as a result of your colleagues’ comments. You are not required to post these final insights.
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