Case Study 1: Fluoroquinolone Antibiotics
Laverne OHara is a 76-year-old patient who was diagnosed with a recurrent cough with sputum
production. She has smoked for more than 50 years. The primary care physician prescribed
amoxicillin/clavulanate (Augmentin) without success. Following a sputum culture, S. pneumonia
was identified. Ms. OHara was then prescribed second-line therapy levofloxacin (Levoquin) for
14 days.
2. What is the recommended dose according to Up-To-Date?
3. What are the pharmacokinetics, pharmacodynamics, and pharmacotherapeutics of the
fluoroquinolone antibiotics? (Address the action, use, contraindications, drug-to-drug, and
drug-to-food interaction, adverse effects, and patient teaching/nursing interventions.)
4. What patent teaching will you provide?
5. During your patient interview with Mrs. OHara, she states she is taking warfarin for atrial
fibrillation. How will this affect the levofloxacin?
Rubric:- Drug Action and Use- Drug Absorption, Metabolism, Distribution, Excretion- Drug Adverse Effects, Contraindications, Precautions, Drug to Drug Interactions, and Drug to Food Interactions, and Drug to Herb Interactions- Drug Administration Guidelines- Clinical Drug Dosing- Patient EducationNo cover page.
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